L-threo-PDMP上海惠诚生物科技有限公司17715331663 021-60496554
货号 | H1749 |
化学名称 | L-threo-PDMP |
CAS Number | 109836-81-9 |
Category | synthetic |
分子式 | C23H38N2O3?HCl |
分子量 | 427 |
规格 | 10mg |
性状 | solid |
纯度 | 98+% TLC |
别名 | L-threo-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol?HCl |
溶剂 | ethanol, methanol |
保存温度 | -20°C |
文献引用 | 1. R. Vunnam, N. Radin “Analogs of ceramide that inhibit glucocerebroside synthetase in mouse brain” Chem Phys Lipids, Vol. 26(3) pp. 265-278, 1980 2. N. Radin et al. “Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells” Journal of Cellular Physiology, Vol. 141(3) pp. 573–583, 1989 3. J. Inokuchi, S. Usuki and M. Jimbo “Stimulation of Glycosphingolipid Biosynthesis by L-Threo-1-Phenyl-2-Decanoylamino-1-Propanol and Its Homologs in B16 Melanoma Cells” J. Biochem, Vol. 117(4) pp. 766-773, 1995 4. N. Radin, et al. “Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth” Journal of Lipid Research, Vol. 36 pp. 611-621, 1995 5. D. Sillance et al. “Glucosylceramide modulates membrane traffic along the endocytic pathway” Journal of Lipid Research, Vol. 43 pp. 1837-1845, 2002 |
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